Friday, May 15, 2009

Darunavir




In the US, Darunavir (darunavir systemic) is a member of the drug class protease inhibitors and is used to treat HIV Infection.

US matches:

  • Darunavir

  • Darunavir Ethanolate

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

J05AE10

CAS registry number (Chemical Abstracts Service)

0206361-99-1

Chemical Formula

C27-H37-N3-O7-S

Molecular Weight

547

Therapeutic Categories

Antiviral agent

Antiviral agent, treatment of HIV infection

Chemical Names

N-((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(3.3.0)oct-2-yloxy)carboxamide

((1S,2R)-3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2R)-1-benzyl-2-hydroxy-3-(N¹-isobutylsulfanilamido)propyl]carbamate (WHO)

Foreign Names

  • Darunavirum (Latin)
  • Darunavir (German)
  • Darunavir (French)
  • Darunavir (Spanish)

Generic Names

  • Darunavir (OS: USAN)
  • TMC-114 (IS: Tibotec)
  • UIC 94017 (IS)
  • TMC 114 (IS: Tibotec)

Brand Names

  • Prezista
    Janssen, Spain; Janssen, Luxembourg; Janssen, Slovenia; Janssen-Cilag International, Austria; Janssen-Ortho Inc., Canada; Centocor, United States; Janssen, Antigua & Barbuda; Janssen, Netherlands Antilles; Janssen, Australia; Janssen, Aruba; Janssen, Barbados; Janssen, Belgium; Janssen, Bermuda; Janssen, Bahamas; Janssen, Germany; Janssen, Grenada; Janssen, Guyana; Janssen, Hungary; Janssen, Ireland; Janssen, Italy; Janssen, Jamaica; Janssen, Saint Kitts & Nevis; Janssen, Cayman Islands; Janssen, Saint Lucia; Janssen, Saint Lucia; Janssen, Netherlands; Janssen, Norway; Janssen, New Zealand; Janssen, Suriname; Janssen, Turks & Caicos Islands; Janssen, Trinidad & Tobago; Janssen, Saint Vincent & The Grenadines; Janssen, Virgin Islands (British); Janssen Pharmaceutical K.K., Japan; Janssen-Cilag, Switzerland; Janssen-Cilag, Denmark; Janssen-Cilag, France; Janssen-Cilag, United Kingdom; Johnson & Johnson, Croatia (Hrvatska)


  • PREZISTA
    Janssen-Cilag, Sweden

International Drug Name Search

Glossary

ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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