Wednesday, February 29, 2012

unoprostone ophthalmic


Generic Name: unoprostone ophthalmic (uh no PROSS tone)

Brand Names: Rescula


What is unoprostone ophthalmic?

Unoprostone ophthalmic reduces pressure in the eye by increasing the amount of fluid that drains from the eye.


Unoprostone ophthalmic is used to treat certain types of glaucoma and other causes of high pressure inside the eye.

Unoprostone ophthalmic may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about unoprostone ophthalmic?


Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using unoprostone before putting your contact lenses in.

Unoprostone ophthalmic may cause a gradual change in the color of your eyes or eyelids and lashes, as well as increased growth or thickness of your eyelashes. These color changes, usually an increase in brown pigment, occur slowly and you may not notice them for months or years. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. This could result in a cosmetic difference in eye or eyelash color from one eye to the other.


Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

After using this medication, wait at least 5 minutes before using any other eye drops that your doctor has prescribed.


What should I discuss with my health care provider before using unoprostone ophthalmic?


Do not use this medication if you are allergic to unoprostone.

Before using unoprostone, tell your doctor if you are allergic to any drugs, or if you have swelling or infection of your eye.


Unoprostone ophthalmic may cause a gradual change in the color of your eyes or eyelids and lashes, as well as increased growth or thickness of your eyelashes. These color changes, usually an increase in brown pigment, occur slowly and you may not notice them for months or years. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. This could result in a cosmetic difference in eye or eyelash color from one eye to the other.


FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether unoprostone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use unoprostone ophthalmic?


Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using unoprostone before putting your contact lenses in.

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.


Wash your hands before using the eye drops.

To apply the eye drops:



  • Tilt your head back slightly and pull down on the lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper. Squeeze out a drop and close your eye. Gently press your finger to the inside corner of the eye (near the nose) for about 1 minute to keep the liquid from draining into your tear duct.




  • If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop. Also wait at least 5 minutes before using any other eye drops that your doctor has prescribed.




Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye. At any time during your use of unoprostone ophthalmic, tell your doctor at once if you have an eye injury, if you develop an eye infection, or if you plan to have eye surgery. Do not use the eye drops if the liquid changes colors or has particles in it. Store the drops at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?


If you forget to use the eye drops, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of unoprostone ophthalmic used in the eyes is not expected to produce life-threatening symptoms.


What should I avoid while using unoprostone ophthalmic?


Avoid using too much of this medication, which can actually make it less effective in lowering the pressure inside the eye.

Avoid using any eye drop medicine that has not been prescribed by your doctor.


Unoprostone ophthalmic side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using unoprostone ophthalmic and call your doctor at once if you have any of these serious side effects:

  • redness, swelling, itching, or pain in or around your eye;




  • oozing or discharge from your eye;




  • increased sensitivity to light; or




  • vision changes.



Less serious side effects may include:



  • cold or flu symptoms such as fever, chills, runny nose, sore throat, cough, diarrhea, and body aches;




  • headache, dizziness;




  • mild eye discomfort;




  • blurred vision;




  • feeling like something is in your eye;




  • dry or watery eyes; or




  • stinging or burning of the eyes after using the drops.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.


Unoprostone ophthalmic Dosing Information


Usual Adult Dose for Intraocular Hypertension:

Instill 1 drop into the affected eye(s) twice daily.

Usual Adult Dose for Glaucoma (Open Angle):

Instill 1 drop into the affected eye(s) twice daily.


What other drugs will affect unoprostone ophthalmic?


There may be other drugs that can affect unoprostone ophthalmic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More unoprostone ophthalmic resources


  • Unoprostone ophthalmic Side Effects (in more detail)
  • Unoprostone ophthalmic Dosage
  • Unoprostone ophthalmic Use in Pregnancy & Breastfeeding
  • Unoprostone ophthalmic Drug Interactions
  • Unoprostone ophthalmic Support Group
  • 0 Reviews for Unoprostone - Add your own review/rating


  • Rescula Advanced Consumer (Micromedex) - Includes Dosage Information



Compare unoprostone ophthalmic with other medications


  • Glaucoma, Open Angle
  • Intraocular Hypertension


Where can I get more information?


  • Your pharmacist can provide more information about unoprostone ophthalmic.

See also: unoprostone side effects (in more detail)


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